Diego Molano

Juan (voice)

Miggs Perez

Xipe (voice)

Spencer Rothbell

Additional Voices (voice) · Miguelito / Trader Josefino (voice)

Haley Mancini

Lana (voice)

Sean-Ryan Petersen

Bellhop #3 (voice)

Paco Galvez

Additional Voices (voice)

Tony Plana

El Pintor (voice)

Fryda Wolff

Talon (voice)

Erica Lindbeck

Caw (voice)

Maria Bamford

Guadelupe (voice)

James Arnold Taylor

Mustache (voice) · Chip (voice)

Olivia Trujillo

Matty (voice)

Kevin Michael Richardson

El Colorado (voice) · Larry Ladron (voice)

Coati Mundi

Hector (voice)

Marcela Bordes

Additional Voices (voice)

Isaac Sandoval

DJ Antonio (voice)

Vanessa Marshall

Lechuza (voice) · La Llorona (voice)

Enrique Tito Contreras

Emilio (voice)

Rocco Narva

El Silbon (voice)

Eric Bradley

El Silbon / Victor (whistling) (voice)

Max Mittelman

Additional Voices (voice)

Rafael Sigler

Juan Lindo (voice)

John DiMaggio

Alfonso (voice)

Dante Basco

Javier (voice)

Debi Derryberry

Cacao (voice)

Marissa Loren

Sofia (voice)

Montse Hernandez

Cristina (voice) · Tula (voice)

Alan Ituriel

Black Hat (voice)

Todd Asayer

Dr. Flug (voice)

Melaney Sems

Demencia (voice)

Parker Simmons

Team Captain (voice)

Xolo Maridueña

Andres (voice) · Additional Voices (voice)

Eric Bauza

Hype Man (voice) · Rick / Richard (voice)

Carolina Ravassa

Itzel (voice) · Tula's Mom (voice)

Fred Tatasciore

Mictlan (voice) · Botero (voice)

Erica Luttrell

Alma / Rosanna (voice) · Toni / Jaime (voice)

Renée Victor

Delores (voice)

Jorge Gutiérrez

Sal (voice)

Dee Bradley Baker

Mictlantecuhtli (voice) · Cammy (voice)

Ryan Lopez

Manuelito (voice)

Daran Norris

Mic / Hun (voice) · Mic (voice)

Arnie Pantoja

Pilli (voice)

Christian Lanz

Tez / Jaguar (voice) · Achi / Dante (voice)

Francisco Ramos

Rey (voice)

George López

José Guadalupe Posada (voice)

Yuri Lowenthal

Baker / Flat Top (voice) · Moreno (voice)

Susana Ballesteros

La Catrina (voice)

Jason Hightower

Don Jalapeño / Li'l Smiley (voice)

Cristina Milizia

Additional Voices (voice)

Arianna Villavicencio

Rosita (voice)

Keith Ferguson

Teo (voice)

Tom Kenny

Guillermo / Boring Guy (voice)

Felipe Esparza

El Bigote (voice)

Miguel Ángel López Díaz

Rey Misterio (voice)

Nathalia Hencker

Reyna (voice)

Oscar Montoya

Ramon (voice)

Cristina Valenzuela

Xochi / Lady 1 (voice) · Xochi / Gal 2 (voice)

Laura Patalano

Grandma Chata / Big Mama (voice)

Carlos Alazraqui

Miguelito / La Pulga (voice) · Miguelito (voice)

Danny Trejo

Paco (voice)

Frankie Quiñones

Maria Teresa / Clerkman (voice) · Nacho (voice)

Eric Lopez

Gustavo (voice) · Gustavo / Emilio (voice)

Jenny Lorenzo

Lupe (voice) · Lupe / La Planchada (voice)

Alex Cazares

Amabel (voice)

David Gallegos

Jorge / Rogrigo (voice)

Elisabeth Garcia

Mariachi (voice)

Linda Uhila

Mariachi (voice)

Laurita Peña

Mariachi (voice)

Angélica Hernández

Mariachi (voice)

Paul Douglas

Paul (voice)

Carl Jones

Cacao / Additional Voices (voice)