Eva Green

Vanessa Ives

Josh Hartnett

Ethan Chandler

Timothy Dalton

Sir Malcolm Murray

Harry Treadaway

Dr. Victor Frankenstein

Reeve Carney

Dorian Gray

Rory Kinnear

John Clare / The Creature

Billie Piper

Lily / Brona Croft

Danny Sapani

Sembene

Helen McCrory

Madame Kali

Olivia Llewellyn

Mina Harker

Simon Russell Beale

Ferdinand Lyle

Wes Studi

Kaetenay

Patti LuPone

Dr. Seward

Alex Price

Proteus

Mary Murray

Woman #1

Owen Roe

Colonel Brewster

Gus Barry

Young Victor

Olivia Fahy

Cowgirl

Aoife Quinn

Somnolent Woman

Alun Armstrong

Vincent Brand

Amy De Bhrún

Prostitute

Jade Yourell

Lady Roxbury

Michael O'Flaherty

Police Sergeant

Mary Stockley

Caroline

Gail Fitzpatrick

Tavern Woman

Hannah Tointon

Maud Gunneson

Leticia Dolera

Lady at the Séance (uncredited)

Tamsin Topolski

Lavinia Putney

Pagan McGrath

Gladys' Maid

Noah Jupe

Charles Chandler

Jack Hickey

Junior Inspector

Elif Knight

Beggar Woman

Sebastian Croft

Boy Familar

Bobby Aherne

Theatre Heckler / Rat-baiting Referee

Jessica Barden

Justine

Perdita Weeks

Catriona Hartdegen

Douglas Hodge

Bartholomew Rusk

Sarah Greene

Hecate Poole

Brian Cox

Jared Talbot

Shazad Latif

Dr. Henry Jekyll

Samuel Barnett

Renfield

Christian Camargo

Dr. Alexander Sweet

David Haig

Oscar Putney

Ruth Gemmell

Octavia Putney

Nicole O'Neill

Witch #1

Olivia Chenery

Witch #2

Charlotte Beckett

Beautiful Witch

Noni Stapleton

Gladys Murray

Morgan C. Jones

Broker

David Haig

Oscar Putney

Stephen Lord

Warren Roper

Jonny Beauchamp

Angelique

Dave Curry

Father

Aideen Wylde

Mother

Rachael Dowling

Dress Shop Owner

Graham Butler

Peter

Amber Fernée

Clare Chandler

Tantoo Cardinal

Old Native American Woman

Hayley Canham

Girl Outside Church

Ronan Vibert

Sir Geoffrey Hawkes

Frank Smith

Curator

Adam William Cahill

Red Coat Soldier (uncredited)

Nathan O'Toole

Ernest

Anna Chancellor

Claire Ives