Fred Tatasciore

Pacha (voice)

J.P. Manoux

Kuzco (voice)

John Goodman

Pacha (voice)

Patrick Warburton

Kronk (voice)

Curtis Armstrong

Mr. Moleguaco (voice)

Justin Cowden

Guaca (voice)

Rip Taylor

The Royal Record Keeper (voice)

Shane Baumel

Tipo (voice)

Bob Bergen

Bucky (voice)

Jessica DiCicco

Malina (voice)

Eartha Kitt

Yzma (voice)

Brenda Song

Dancing Queen (voice)

Cole Sprouse

Zim (voice)

Miley Cyrus

Mudka (voice)

Gabriel Iglesias

Yu / Tu (voice; uncredited)

Candi Milo

Ms. Oopatral (voice)

Kevin Michael Richardson

Kavo (voice; uncredited)

Patti Deutsch

Mata (voice)

Tress MacNeille

Mrs. Upachal (voice)

Tom Kenny

Narrator (voice)

Courtney Peldon

Cuxi / Curi / Cuca (voice)

Michaela Jill Murphy

Chaca (voice)

Mark Schiff

Urkon (voice)

Jeff Bennett

Topo / Ipi (voice)

Frank Welker

Homework the Cat (voice)

Dylan Sprouse

Zam (voice)