Will Forte

Abe Lincoln / Narrator (voice)

Phil Lord

Principal Dr. Cinnamon J. Scudworth (voice)

Michael McDonald

Gandhi (voice)

Christa Miller

Cleopatra (voice)

Christopher Miller

JFK / Mr. Butlertron (voice)

Nicole Sullivan

Joan of Arc (voice)

Judah Miller

Inmate (voice)

Murray Miller

Catherine the Great (voice)

Bill Lawrence

The Shadowy Figure (voice) (uncredited)

Michael J. Fox

Gandhi's Remaining Kidney (voice)

Mandy Moore

Mandy Moore (voice)

Luke Perry

Ponce de León (voice)

John C. McGinley

Creepy Trucker (voice)

Chris Berman

Chris Berman (voice)

John Stamos

John Stamos (voice)

Jack Black

Pusher / Larry Hardcore (voice)

Ashley Parker Angel

Ashley Parker Angel (voice)

Zach Braff

X-Stream Mike (voice)

Tom Green

Tom Green (voice)

Debra Wilson

Girl in Commercial (voice)

Sarah Chalke

Marie Antoinette (voice)

Joe Flaherty

Abe’s Foster Dad (voice)

Andy Dick

Mr. Sheepman / Thomas Edison / Sexual Education Officer (voice) · Van Gogh (voice)

Marilyn Manson

Marilyn Manson (voice) (uncredited)

Dan Patrick

Dan Patrick (voice)

Neil Flynn

E-CyboPooch / Pirate / Rich Man / Moses (voice)

Donald Faison

Toots / Wally (voice)

Jeffrey Garcia

Jesús Cristo (voice)

Tommy Walter

Abandoned Pools (voice)