Will Smith

Capt. James West

Kevin Kline

U.S. Marshal Artemus Gordon / President Grant

Kenneth Branagh

Dr. Arliss Loveless

Salma Hayek Pinault

Rita Escobar

M. Emmet Walsh

Coleman

Ted Levine

General 'Bloodbath' McGrath

Frederique van der Wal

Amazonia

Musetta Vander

Munitia

Sofia Eng

Miss Lippenrieder

Bai Ling

Miss Mae Lee East

Garcelle Beauvais

Belle (Girl in Water Tower)

Mike H. McGaughy

Big reb

Jerry Wills

Other Reb

Rodney A. Grant

Hudson

Buck Taylor

Cross-Eyed Reb

E.J. Callahan

Mr. Pinkerton

Debra Christofferson

Dora Look-Alike

James Lashly

Reb #1

Dean Rader Duval

Reb #2

Christian Aubert

French Dignitary

Orestes Matacena

Spanish Dignitary

Ian Abercrombie

British Dignitary

Ismael 'East' Carlo

Mexican Dignitary

Bob Rumnock

White House Aide

Gary Carlos Cervantes

Dr. Guillermo Escobar

Jerry Potter

George Washington

Mik Scriba

Guard

Michael Sims

Prof. Thaddeus Morton

J.J. Perry

Shovel Guy (uncredited)

Dennis Keiffer

Wrench Guy (uncredited)

Derek Mears

Metal Head (uncredited)