Keir Gilchrist

Craig Gilner

Emma Roberts

Noelle

Zach Galifianakis

Bobby

Viola Davis

Dr. Eden Minerva

Lauren Graham

Lynn Gilner

Jim Gaffigan

George Gilner

Jeremy Davies

Smitty

Zoë Kravitz

Nia

Bernard White

Muqtada

Thomas Mann

Aaron Fitzcarraldo

Matthew Maher

Humble

Adrian Martinez

Johnny

Aasif Mandvi

Dr. Mahmoud

Novella Nelson

Professor

Dana DeVestern

Alyssa Gilner

Karen Chilton

Nurse Harper

Rosalyn Coleman

Monica

Daniel London

Solomon

Leo Allen

Mr. Reynolds

Mary Birdsong

Bobby's Ex

Morgan Murphy

Joanie

Billy McFadden

Little Craig

Jared Goldstein

Ronny

Alan Aisenberg

Scuggs

Lou Myers

Jimmy

MacIntyre Dixon

Roger

Molly Hager

Becca

Ato Blankson-Wood

Jennifer

Caitlin Kinnunen

Science Geek

Ben Folstein

Neil

Stephen Scott Scarpulla

HS Director

Jee Young Han

HS Do-Gooder

Stewart Steinberg

Charlie

Roddy Skeaping

Acteur

Susan Blommaert

HS Teacher

Ethan Herschenfeld

Acid Head

Kenya Brome

Under Pressure Nurse #2