Judd Nelson

Hot Rod / Rodimus Prime (voice)

Shia LaBeouf

Sam Witwicky

Megan Fox

Mikaela Banes

Peter Cullen

Optimus Prime / Ironhide (voice) · Optimus Prime (voice)

Frank Welker

Soundwave / Megatron / Rumble / Frenzy / Wheelie (voice)

Mark Ryan

Bumblebee (voice)

Leonard Nimoy

Galvatron (voice)

Hugo Weaving

Megatron (voice)

Orson Welles

Unicron (voice)

Casey Kasem

Cliffjumper (voice)

Josh Duhamel

Captain Lennox

Dan Gilvezan

Bumblebee (voice)

Tyrese Gibson

USAF Tech Sergeant Epps

Charlie Adler

Starscream (voice)

Scatman Crothers

Jazz (voice)

Rachael Taylor

Maggie Madsen

Susan Blu

Arcee (voice)

Anthony Anderson

Glen Whitmann

Eric Idle

Wreck-Gar (voice)

Jon Voight

Defense Secretary John Keller

Robert Stack

Ultra Magnus (voice)

John Turturro

Agent Simmons

Norman Alden

Kranix (voice)

Jack Angel

Astrotrain (voice)

Michael O'Neill

Tom Banacheck

Kevin Dunn

Ron Witwicky

Michael Bell

Prowl / Scrapper / Swoop / Junkion (voice)

Gregg Berger

Grimlock (voice)

Julie White

Judy Witwicky

Amaury Nolasco

ACWO Jorge 'Fig' Figueroa

Lionel Stander

Kup (voice)

John Moschitta Jr.

Blurr (voice)

Zack Ward

First Sergeant Donnelly

Buster Jones

Blaster (voice)

Luis Echagarruga

Ranger Team

Bud Davis

Dirge (voice)

Patrick Mulderrig

Ranger Team

Brian Shehan

Ranger Team

Walker Edmiston

Inferno (voice)

Michael Trisler

Ranger Team

Paul Eiding

Perceptor (voice)

Ashkan Kashanchi

Mahfouz

Neil Ross

Bonecrusher / Hook / Springer / Slag (voice)

Corey Burton

Spike / Brawn / Shockwave (voice)

Rizwan Manji

Akram

Roger C. Carmel

Cyclonus / Quintesson Leader (voice)

William Morgan Sheppard

Captain Witwicky

Arthur Burghardt

Devastator (voice)

C.J. Thomason

Sailor

Bernie Mac

Bobby Bolivia

Don Messick

Gears (voice)

Carlos Moreno Jr.

Manny

Ed Gilbert

Blitzwing (voice)

Clive Revill

Kickback (voice)

Johnny Sanchez

Clown

Hal Rayle

Shrapnel (voice)

John Robinson

Miles

David Mendenhall

Daniel (voice)

Travis Van Winkle

Trent

Peter Jacobson

Mr. Hosney

Victor Caroli

Narrator (voice)

Glenn Morshower

SOCCENT Sergeant

Stan Jones

Scourge (voice)

Christopher Collins

Starscream / Laserbeak (voice)

Frederic Doss

SOCCENT Op-Centre Tech

Charlie Bodin

SOCCENT Op-Centre Tech

Joshua Feinman

USAF Staff Sergeant

Chris Ellis

Admiral Brigham

Steven Ford

Four Star General

Michael Shamus Wiles

Two Star General

Craig Barnett

Air Force Major General

Brian Prescott

Keller Aide

Brian Stepanek

Sector Seven Agent

Wiley M. Pickett

FBI Agent

Andy Milder

R&D Team Leader

Ravi Patel

Telephone Operator

Rick Gomez

Sheriff

Tom Lenk

Analyst

Jamison Yang

Analyst

Andrew Lewis Caldwell

Café Kid

J.P. Manoux

Witness

Michael Adams

AWACS Controller

Jason White

AWACS Controller

Odette Annable

Socialite

Bob Stephenson

Xbox Guy

Jess Harnell

Ironhide / Barricade (voice)

Reno Wilson

Frenzy (voice)

Michael Bay

Guy Flicked by Megatron (uncredited)

Colton Haynes

Cafe Kid (uncredited)

Omar Benson Miller

Glen's Cousin (uncredited)

James Hunter

Cop (uncredited)