Kristen Stewart

Frankie / Frances

Alia Shawkat

Molly

LaKeith Stanfield

Not Metal Head Dave

Zack Fox

Josh

Tony Hale

Martin Flynn

Chris Estrada

Jose

Thomas La Barbera Christensen

Axel

Thor Knai

Dagmar

Thomas Nicholson

Fritz

Seth Rogen

Dio (voice)

Kumail Nanjiani

GG (voice)

Kate McKinnon

Dr. Olsen

Geena Davis

Dr. Chapman

Cate Blanchett

Deep Sea Expert (voice)

Taj Cross

Kai

Morgan Krantz

Mike Z

Sugar Lyn Beard

Mr. Kock

Zed Cutsinger

Young Martin Flynn

Marissa "Missy" Dabice

Mannequin Pussy

Kaleen Reading

Mannequin Pussy

Colins Regisford

Mannequin Pussy

Maxine Steen

Mannequin Pussy