Emily Blunt

Liza Drake

Chris Evans

Pete Brenner

Catherine O'Hara

Jackie

Andy Garcia

Dr. Neel

Jay Duplass

Larkin

Brian d'Arcy James

Dr. Lydell

Amit Shah

Eric Paley

Chloe Coleman

Phoebe

Valerie LeBlanc

Laurene

Aubrey Dollar

Andy

Alex Klein

Sidney

Britt Rentschler

Camille

Michael Kosta

Guy Schatz

Nicholas Christopher McNeil

Randy

Bella Winkowski

Luna

Chapel Oaks

Daughter

Elle Lisic

Daughter

Willie Raysor

Matt

Selena Anduze

Kate

Josh Ventura

Dr. Jimmy

A.K. Benninghofen

Dr. Bowen

Chinet Scott

Nicole

Avis-Marie Barnes

Principal

Mike Stoudt

Banker

Lydia Castro

Banker

Nicole Sellars

Zanna Presenter

Adrian Enrique Hernandez

Clinic Receptionist

Rebecca Barnes

Clinic Office Staffer

Mandi Christine Kerr

Clinic RN

Joseph Mazza

Neurologist

Neil Kelly

Jason

Samantha Kacho

Catherine

Darryl L. Dillard

Podiatrist

Rowan Joseph

Podiatrist

Chris Marks

Jeff

Erica-Marie Sanchez

Applicant

Becca Breitfeller

Applicant

Andrea Laing

Ellen

Adrian Eppley

Heather

Greyson Chadwick

Maria

Hillary Harley

Tina

Pat Dortch

Nervous Pain Clinic Doctor

Jeffrey Charles Morgan

Middle Aged Doctor

Jay Pearson

Georgia Doctor

Colby Burton

Ryan

Omer Mughal

Agent Simonetti

Cara Mantella

Admissions Officer

Dustin Lewis

Mr. Jorgenson

Mary Ann Hagan

Patient Outside Lydell's Clinic

Helen Ingebritsen

Patient Outside Lydell's Clinic

Alex Van

Patient Outside Lydell's Clinic

Quinn Bozza

Undercover D.E.A.

Donna DuPlantier

Jane Yagoda

Michael Lowry

Neel's Lawyer

Carolyn Jones Ellis

Adrienne's Mom

Ryan King

Sam Walter's Husband

David Kronawitter

Dr. Hartigan

Leydi Morales

Loan Agent

Jackson Abram

Matt's Son

Maria Sager

Neel's Housekeeper

Brandon Stanley

Drama Teacher

Erin Ownbey

Young Jackie

Snowden Grey

Cinda

Alan Wells

Gambling Anonymous Doctor

Cliff Lanning

Crooning Doctor

Sharon Conley

Judge Susan Holman

Desmond Phillips

Bartender

Nick Arapoglou

Bartender

Alexis Baca

Pharmaceutical Model (uncredited)