Will Ferrell

Harold Crick

Maggie Gyllenhaal

Ana Pascal

Dustin Hoffman

Professor Jules Hilbert

Emma Thompson

Karen Eiffel

Queen Latifah

Penny Escher

Tony Hale

Dave

Tom Hulce

Dr. Cayly

Linda Hunt

Dr. Mittag-Leffler

Kristin Chenoweth

Book Channel Host

John M. Watson Sr.

TV Author

William Dick

IRS Co-Worker #1

Guy Massey

IRS Co-Worker #2

Martha Espinoza

IRS Co-Worker #3

T.J. Jagodowski

IRS Co-Worker #4

Peter Grosz

IRS Co-Worker #5

Tonray Ho

IRS Co-Worker #6

Herb Lichtenstein

IRS Co-Worker #7

Stacey Elaine Jackson

IRS Co-Worker #8

Ricky Adams

Young Boy

Christian Stolte

Young Boy's Father

Denise Hughes

Kronecker Bus Driver

Peggy Roeder

Polish Woman

Danny Rhodes

Bakery Employee #1

Linara Washington

Bakery Employee #2

翁杏蘭

Bakery Customer #1

David Pompeii

Bakery Customer #2

David Wiegers

Bakery Customer #3

Jarrett Sleeper

Bakery Customer #4

Larry Neumann Jr.

Homeless Man

John Mohrlein

Man with Hose

Bruce Jarchow

Commuter

Bradley Mott

Large Man on Bus

Karen Lloyd

Customer with Tan

Keith Kupferer

Demolition Foreman

Danny McCarthy

Demolition Crew #1

Tab Baker

Demolition Crew #2

Mark Buettner

Claw Operator

Christian Young

ER Doctor #1

Ray Kurut

ER Doctor #2

Michael Cook

ER Doctor #3

Celeste Pechous

ER Nurse #2

Chet Dubowski

Man in Tweed

Ora Jones

Banneker Press Receptionist

Nadirah Bost

Accident Witness

Frank Caeti

Accident Witness

Andrew Rothenberg

Doctor Mercator

Rengin Altay

Nurse

Bob Papenbrook

Animal Footage Voice Over (voice)

Sia A. Moody

Nurse #3 (uncredited)

Eli Goodman

Augustus Chatman (uncredited)