Marlon Brando

Dr. Moreau

Val Kilmer

Montgomery

David Thewlis

Douglas

Fairuza Balk

Aissa

Ron Perlman

Sayer of the Law

Marco Hofschneider

M'Ling

Temuera Morrison

Azazello

William Hootkins

Kiril

Daniel Rigney

Hyena-Swine

Nelson de la Rosa

Majai

Peter Elliott

Assassimon

Mark Dacascos

Lo-Mai

Miguel López

Waggdi

Neil G. Young

Boar Man

David Hudson

Bison Man

Clare Grant

Fox Lady

Kitty Silver

Sow Lady #1

Fiona Mahl

Sow Lady #2

Agoes Widjaya Soedjarwo

Captain

Ron Vreeken

Soldier #1

Lou Horváth

Soldier #2

Frank Welker

Assassimon (voice) (uncredited)

Richard Stanley

Bulldog Man (uncredited)

Morgan Smallbone

Dog Man (uncredited)