Matthew Broderick

Inspector Gadget / Robogadget / John Brown

Rupert Everett

Sanford Scolex

Joely Fisher

Brenda / Robobrenda

Michelle Trachtenberg

Penny

Andy Dick

Kramer

Cheri Oteri

Mayor Wilson

Mike Hagerty

Sikes

Dabney Coleman

Chief Quimby

D.L. Hughley

Gadgetmobile (voice)

René Auberjonois

Artemus Bradford

Frances Bay

Thelma

Mr. T

Mr. T

Richard Kiel

Famous Big Guy with Silver Teeth

Richard Lee-Sung

Famous Villain with Deadly Hat

Bobby Bell

Famous Identifier of Sea Planes

Hank Barrera

Famous Native American Sidekick

Keith Morrison

Famous Assistant to Dr. Frankensomething

John Kim

Son Before Second Son

Aaron Meyerson

Aaron Meyerson

Cliff Emmich

Out of Control Bus Driver

Jennifer Ingersoll

In Terrible Jeopardy Young Girls

Haley Harper

In Terrible Jeopardy Young Girls

Vichany Sam

In Terrible Jeopardy Young Girls

Ivory Dilley

In Terrible Jeopardy Young Girls

Brielle Blunt

In Terrible Jeopardy Young Girls

Hailey Peitzman

In Terrible Jeopardy Young Girls

Brian Tibbetts

Amazed Boy on Bike

Bob Gaynor

Robotic Foot Dancer

Richard Penn

Fantastic Doctor

J.P. Manoux

Mayor's Sychophantic Assistant

Sam Brown

Officer McMurphy

Brad Blaisdell

Officer Johnson

Sonya Eddy

Hospital Secretary

Katsy Chappell

Nurse in Hallway

Kathleen M. Darcy

Nurse in Hallway

Brian George

Sore Guru

Alexander Witt

Wet, Green Businessman

E.J. Callahan

Hot Dog Vendor

Chad Parker

Assistant Car Thief

Mary Chris Wall

Snoopy News Anchor

James Thiel

Twin Bartender

Jeff Thiel

Twin Bartender

Andy Heyward

Mr. DIC

Matt Murray

Scared Witless Autograph Dad

Mark Leahy

Kid's Angry Father

Tadao Tomomatsu

Bewildered Japanese Tourist

Adrienne Wehr

Waitress on Bridge

Don Adams

Brain (voice)

Danny Nero

Police Officer (uncredited)