Oscar Isaac

Victor Frankenstein

Robert De Niro

The Creature / Sharp Featured Man

Jacob Elordi

The Creature

Kenneth Branagh

Victor Frankenstein

Christoph Waltz

Harlander

Tom Hulce

Henry Clerval

Helena Bonham Carter

Elizabeth

Mia Goth

Elizabeth / Claire Frankenstein

Aidan Quinn

Cap. Robert Walton

Felix Kammerer

William Frankenstein

Charles Dance

Leopold Frankenstein

Ian Holm

Baron Frankenstein

David Bradley

Blind Man

Richard Briers

Grandfather

John Cleese

Prof. Waldman

Lars Mikkelsen

Captain Anderson

Christian Convery

Young Victor Frankenstein

Robert Hardy

Prof. Krempe

Cherie Lunghi

Caroline Beaufort Frankenstein

Nikolaj Lie Kaas

Chief Officer Larsen

Celia Imrie

Mrs. Moritz

Kyle Gatehouse

Young Hunter

Lauren Collins

Hunter's Wife

Trevyn McDowell

Justine

Mark Hadfield

Felix

Sofia Galasso

Anna-Maria

Gerard Horan

Claude

Joachim Fjelstrup

Dr. Udsen

Joanna Roth

Marie

Ralph Ineson

Professor Krempe

Alfred Bell

Landlord

Peter Millard

Professor Stokeld

Peter MacNeill

Professor Maurus

Sasha Hanau

Maggie

Burn Gorman

Executioner

Joseph England

Thomas

Richard Clifford

Minister

Sean Sullivan

Old Hunter #1

George Asprey

Policeman

Stuart Hughes

Old Hunter #2

Gord Rand

Silversmith

Hugh Bonneville

Schiller

Kenton Craig

Harlander's Butler

Ryan J-W Smith

William

Charles Wyn-Davies

Young William

Val Ovtcharov

Outpost Clerk

Anders Yates

Torfussen

Rory Jennings

Young Victor

Adam Brown

Prisoner #1

Christina Cuttall

Young Justine

Hannah Taylor-Gordon

Young Elizabeth

Santiago Segura

Prisoner #2

Dexter Stokes-Mellor

Prisoner #3

Susan Field

Frau Brach

Jimmy Yuill

Greigori

Shian Denovan

Nymph

Chris Barnes

Ship's Crew

Mark Steger

Spinal Corpse

Rafe Harwood

Young William Frankenstein

Shaun Prendergast

Ship's Crew

Gregory Mann

Head Urchin

Tommy Wright

Ship's Crew

David Kennedy

Ship's Crew

Roberto Campanella

Dark Angel

Paul Gregory

Ship's Crew

Rebecca Lawson-Turner

Woman in Confessional

Chris Hollis

Ship's Crew

Warren Albert

Professor Kugelmann

Kim Morgan

Guest at Wedding and Bistro

Robin Lloyd

Ship's Crew

Alex Lowe

Ship's Crew

Chris Andrews

Bistro Dancer

Graham Loughridge

Ship's Crew

Lewis Landini

Bistro Dancer

Simon Cox

Ship's Crew

William John Banks

Bistro Dancer

Robert Hines

Ship's Crew

Tess Letham

Bistro Dancer

Alexandros Beshonges

Bistro Dancer

Lonnie James

Rough Woman

Jenny Galloway

Vendor's Wife

Edward Jewesbury

City Official

Siobhan Redmond

Midwife

Angus Wright

Guard

Max Gold

Servant

Frank Meschkuleit

Additional Performances (puppeteer)

Dudi Appleton

Mansion Staff

Jim Carter

Executioner (uncredited)