Clint Eastwood

Manco

Lee Van Cleef

Col. Douglas Mortimer

Gian Maria Volonté

El Indio

Mara Krupp

Mary

Luigi Pistilli

Groggy, Member of Indio's Gang

Klaus Kinski

Juan Wild - The Hunchback

Luis Rodríguez

Manuel, Member of Indio's Gang

Benito Stefanelli

Luke 'Hughie'

Panos Papadopulos

Sancho Perez, Member of Indio's Gang

Aldo Sambrell

Cuchillo

Roberto Camardiel

Tucumcari Station Clerk

Joseph Egger

Old Prophet

Tomás Blanco

Tucumcari Sheriff

Lorenzo Robledo

Tomaso, Indio's Traitor

Dante Maggio

Carpenter in Cell with El Indio

Sergio Mendizábal

Tucumcari Bank Manager

Diana Rabito

Callaway's Beautiful Girl in Tub

Giovanni Tarallo

Santa Cruz Telegraphist

Mario Meniconi

Train Conductor

Mario Brega

Niño, Member of Indio's Gang

José Terrón

Guy Calloway, Mortimer's 1st Criminal (uncredited)

José Marco

'Baby' Red Cavanaugh (uncredited)

Werner Abrolat

Slim, Member of Indio's Gang (uncredited)

Frank Braña

Blackie, Member of Indio's Gang (uncredited)

José Canalejas

Chico, Member of Indio's Gang (uncredited)

Antonio Molino Rojo

Frisco, Member of Indio's Gang (uncredited)

Jesús Guzmán

Carpetbagger on Train (uncredited)

Ricardo Palacios

Tucumcari Saloon Keeper (uncredited)

Guillermo Méndez

White Rocks Sheriff (uncredited)

Rosemary Dexter

Mortimer's Sister (uncredited)

Peter Lee Lawrence

Mortimer's Brother-in-Law (uncredited)

Kurt Zips

Hotel Manager (uncredited)

Enrique Navarro

Tucumcari Sheriff (uncredited)

Bruno Corazzari

Poker Player (uncredited)

Carlo Simi

El Paso Bank Manager (uncredited)

Antoñito Ruiz

Fernando (uncredited)

Román Ariznavarreta

Half-Shaved Bounty Hunter (uncredited)

Joseph Bradley

El Paso Tavern Keeper (uncredited)

Fernando Di Leo

Cigar Smoking Card Player (uncredited)

Diana Faenza

Tomaso's Wife (uncredited)

Eduardo García

Member of Indio's Gang (uncredited)

Sergio Leone

Whistling Bounty Hunter (voice) (uncredited)