Rainn Wilson

Randy

Lil Rel Howery

Mike

Aimee Carrero

Jessica

Yvette Nicole Brown

Shanice

Rob Riggle

Dr. Serano

Page Kennedy

Officer Taggert

Xolo Maridueña

Rookie

Eric Jungmann

Nurse Chad

Ayesha Harris

Kim

Luka Jones

Motorcycle Matt

Andy Milder

Bruce

Dalia Rooni

Rachel

Cameron Fuller

Jimmy

Michael J. Sielaff

Johnny

Joaquin Veizaga

Vicente

Liam Oh

Chip (uncredited)

Michael Monks

Officer White

Rafael Castillo

Charlie (Mr. President)

Tree O'Toole

Heroin Addict

Therese McLaughlin

Crazy Woman

Peter Holden

Angry White Guy

Melissa Bailey

Charge Nurse

Treisa Gary

Nurse Ruth

Sierra Swartz

Jenna - Sorority Girl

Juan Pacheco

Baseball Coach

Omar Leyva

Vicente's Uncle

Aimee Li

Nurse Colette

Andriana Garbiso

ER Nurse

Adam Mondschein

Drunk Rocky