Cate Blanchett

Bernadette

Billy Crudup

Elgie

Kristen Wiig

Audrey

Judy Greer

Dr. Kurtz

Laurence Fishburne

Paul Jellinek

Emma Nelson

Bee

Troian Bellisario

Becky

James Urbaniak

Agent Marcus Strang

Megan Mullally

Judy Toll

Richard Robichaux

Floyd the Pharmacist

Kate Burton

Ellen Idelson

Steve Zahn

David Walker

David Paymer

Jay Ross

Zoë Chao

Soo-Lin

Patrick Sebes

Tom the Blackberry Guy

Lee Harrington

USC Student

Patrick Jordan

Game Show Host

Shaun Cameron Hall

Pablo

Kathryn Feeney

Tamara the Pharmacy Employee

Amy Rayko

Lisa Prospective Parent

Nancy McNulty

Lori Prospective Parent

Daina Griffith

Julie Prospective Parent

Kate Easton

Tammy Prospective Parent

Stephen Donnelly

Mr. Hayes

Thalia Torio

Kennedy

Mark Philip Stevenson

Architectural Expert

Cherie McClain

News Reporter

Maureen d'Armand

Crew Member Allegra

Jóhannes Haukur Jóhannesson

Captain J. Rouverol

Claudia Doumit

Iris

Katelyn Statton

Vivian

Jennifer Tober

Snappy Tourist Lady

Joe Coyle

Mike the State Senator

Richard Barlow

Stu Reardon (Microsoft Executive) (uncredited)

Tom Bonello

Pharmacy Patron (uncredited)

Brian Bowman

Parent (uncredited)

Gregory Bromfield

Caterer (uncredited)

Zachary Davis Brown

Kyle's Friend (uncredited)

Owen Buckenmaier

Kyle (uncredited)

Isaac J. Conner

Passenger (uncredited)

Bruce Curtis

Nigel Mills-Murray (uncredited)

Kelley Davis

Passenger (uncredited)

Amy Lyn Elliott

Flight Attendant (uncredited)

Joe Fishel

Galer Street School Parent (uncredited)

Emir García

Pedestrian (uncredited)

Edward Pfeifer

Bus Passenger (uncredited)

Noah J. Welter

Jellinek Student (uncredited)

Lana Young

Elaine the Airline Woman (uncredited)

Jean Zarzour

Passenger (uncredited)