Whoopi Goldberg

Jane Deluca

Mary-Louise Parker

Robin

Drew Barrymore

Holly Pulchik-Lincoln

Matthew McConaughey

Abe Lincoln

James Remar

Alex

Billy Wirth

Nick

Anita Gillette

Elaine

Dennis Boutsikaris

Massarelli

Estelle Parsons

Louise

Amy Aquino

Anna

Stan Egi

Henry

Stephen Gevedon

Johnny Figgis/Jane's Band

Amy Ray

Indigo Girl

Emily Saliers

Indigo Girl

Jude Ciccolella

Jerry

Gedde Watanabe

Steve

Jon Seda

Pete

Mimi Toro

Carrie

Lori Alan

Girl with Attitude

Mary Anne McGarry

Dr. Newbauer

Michael Storm

Tommy

Danielle Shuman

Young Robin

Julian Neil

Nightclub Owner

Niecy Nash

Woman at Diner

Ted Zurkowski

Drug Buyer

Jill C. Klein

Waitress

Marnie Crossen

Nurse

Aaron Lustig

Judge

Terri White

Female Guard

George Georgiadis

Cab Driver

Cheryl A. Kelly

Hotel Clerk

Adria Contreras

Mary Todd (5 Months)

Malika Edwards

Mary Todd (10 Months)

Pablo Espinosa

New Mexico Police

Kevin La Presle

New Mexico Police

John F. Manfredonia

Obstetrician

James Shuffield

Gynecologist

Thomas Kevin Danaher

Tuscon Police

Richard Lowell McDole

Tuscon Police

Don Hewitt Sr.

Tow Truck Driver

Tito Larriva

Indigo Girls' Band

Joseph Alfieri

Bartender (voice)