David Kaufman

Stuart Little (voice)

Myles Jeffrey

George Little (voice)

Jennifer Hale

Eleanor Little / Martha Little (voice)

Hugh Laurie

Mr. Frederick Little (voice)

Julie Nathanson

(voice)

André Sogliuzzo

Monty (voice)

Kathy Najimy

Margalo (voice)

Kevin Schon

Snowbell (voice)

Rachael Harris

(voice)

Robert Costanzo

(voice)

Debi Derryberry

(voice)

Dee Bradley Baker

Additional Voices (voice)

Quinton Flynn

Snowbell (voice)

Marc John Jefferies

Will (voice)

Jim Wise

(voice)

Ken Hudson Campbell

(voice)

Daniel Hansen

(voice)

Lacey Chabert

(voice)

Matt Kaminsky

(voice)

Sean Marquette

Zack (voice)

Lauren Tom

(voice)

Edie McClurg

(voice)

Michael Chiklis

Tiger (voice)

Mark Hamill

Falcon (voice)

Simbi Khali

(voice)

Carlos Alazraqui

Monty (voice)

Jeff Bennett

Crows (voice)

Pat Fraley

(voice)

Jeffrey Jones

Uncle Crenshaw Little (voice)

Susan Silo

(voice)